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Volume Regulation of Müller Cells in the Postnatal and Pathologically Altered Retina


Autor(en) / Herausgeber
Antje Wurm
Sprache(n)
Englisch
Erscheinungsdatum
18.03.2009
Verarbeitung
Broschur
Umfang
115 Seiten
ISBN
978-3-86583-316-7
Preis
24.00 €
Dokumente / Vorschau
keine
Lieferstatus
lieferbar
Volume Regulation of Müller Cells in the Postnatal and Pathologically Altered Retina

Volume Regulation of Müller Cells in the Postnatal and Pathologically Altered Retina
Autor(en) / Herausgeber
Antje Wurm
Sprache(n)
Englisch
Erscheinungsdatum
18.03.2009
Verarbeitung
Broschur
Umfang
115 Seiten
ISBN
978-3-86583-316-7
Preis
24.00 €
Dokumente / Vorschau
keine
Lieferstatus
lieferbar
Beschreibung
Based upon 5 peer reviewed publications, this cumulative dissertation provides insights into mechanisms of the volume regulation of Müller cells and the importance thereof for the integrity of the retinal tissue. To this end, Müller cells of the postnatal retina of the rat and Müller cells of pathologically altered retinae were tested for their ability to counteract cellular swelling under hypoosmotic stress. These studies demonstrate that the high membrane conductance for potassium is a prerequisite for an efficient volume regulation of differentiated Müller cells. Moreover, these studies show that Müller cells (which function as the water and potassium 'pumps' of the retina) might be involved in the pathomechanisms resulting in the formation of retinal edema.
weniger
Based upon 5 peer reviewed publications, this cumulative dissertation provides insights into mechanisms of the volume regulation of Müller cells and the importance thereof for the integrity of the ...
mehr
Leipzig Series in Brain Cognition and Language, Antje Wurm, Neurologie, Kognitionswissenschaft